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A Yeast Glycolipid Biosurfactant, Mannosylerythritol Lipid, Shows Potential Moisturizing Activity toward Cultured Human Skin Cells: The Recovery Effect of MEL-A on the SDS-damaged Human Skin Cells
A Yeast Glycolipid Biosurfactant, Mannosylerythritol Lipid, Shows Potential Moisturizing Activity toward Cultured Human Skin Cells: The Recovery Effect of MEL-A on the SDS-damaged Human Skin Cells Abstract Mannosylerythritol lipids (MELs) are produced in large amounts from renewable vegetable oils by Pseudozyma antarctica, and are the most promising biosurfactants known due…
Development of a high-throughput screening system for identifi cation of novel reagents regulating DNA damage in human dermal fibroblasts
Development of a high-throughput screening system for identifi cation of novel reagents regulating DNA damage in human dermal fibroblasts Ultraviolet (UV) radiation is a major inducer of skin aging and accumulated exposure to UV radiation increases DNA damage in skin cells, including dermal fibroblasts. In the present study, we developed…
Ceramide-based nanostructured lipid carriers for transdermal delivery of isoliquiritigenin: Development, physicochemical characterization, and in vitro skin permeation studies
Ceramide-based nanostructured lipid carriers for transdermal delivery of isoliquiritigenin: Development, physicochemical characterization, and in vitro skin permeation studies Abstract An optimized, ceramide-based, nanostructured lipid carrier (NLC) formulation was developed for isoliquiritigenin (ILTG), and its potential as a transdermal delivery system was evaluated. ILTG-loaded NLCs were prepared by blending solid (ceramide,…
Efficacy of an agonist of a-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation
Efficacy of an agonist of a-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation Abstract OBJECTIVE: Hair greying (i.e., canities) is a component of chronological ageing and occurs regardless of gender or ethnicity. Canities is directly linked to the loss of melanin and increase in oxidative stress in the hair follicle and…
Administration of Kakadu Plum Extract (Terminalia ferdinandiana) Cream Prevented the Increase of Tyrosinase Expression and Melanin Amount on Ultraviolet-B Exposed Male Guinea Pigs (Cavia porcellus) Skin
Administration of Kakadu Plum Extract (Terminalia ferdinandiana) Cream Prevented the Increase of Tyrosinase Expression and Melanin Amount on Ultraviolet-B Exposed Male Guinea Pigs (Cavia porcellus) Skin Abstract Background: Hyperpigmentation causes various impacts such as lack of confidence and decreased productivity. The gold standard of hyperpigmentation treatment is using 4% hydroquinone…
A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity
A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity Abstract Background: Collagen is the primary component in human skin. With age, there isloss of skin elasticity and collagen, resulting in wrinkle formation and reduction inskin appearance. Aims: The objective…